Scientific Program

Conference Series Ltd invites all the participants across the globe to attend 4th International Conference and Exhibition on Nutrition Chicago, Illinois, USA.

Day 1 :

Keynote Forum

Ozlem Tokusoglu

Celal Bayar University, Turkey

Keynote: Innovation technologies on nutritional quality and health

Time : 09:00-09:35

OMICS International Nutrition 2015 International Conference Keynote Speaker Ozlem Tokusoglu photo
Biography:

Tokusoglu has completed her PhD at Ege University Engineering Faculty, Dept. of Food Engineering at 2001. She is currently working as Associate Professor faculty member in Celal Bayar University Engineering Faculty Department of Food Engineering. She performed a visiting scholarship at the Food Science and Nutrition Department /University of Florida, Gainesville-Florida-USA during 1999-2000 and as Visiting Professor at the School of Food Science, Washington State University, Pullman, Washington,USA during April-May 2010. She has published many papers in peer reviewed journals and serving as an Editorial Board Member of International Journal of Food Science and Technology (IJFST) by Wiley Publisher, USA and Journal of Food, Agriculture and Environment (JFAE) by WFL Publisher, Finland. She published the scientific edited two book entitled “Fruit and Cereal Bioactives: Chemistry, Sources and Applications” by CRC Press, Taylor & Francis, USA. She is a Publisher for book entitled “Improved Food Quality with Novel Food Processing” by CRC Press, third book “Food By-Product Based Functional Food Powders” is in progress.

Abstract:

The “nutrition” word first appeared in 1551 and comes from the Latin word nutrire, meaning “to nourish.” Currently, it is defined as the sum of all processes involved in how organisms obtain nutrients, metabolize them and use them to support all of life’s processing. Nutritional science covers a wide spectrum of disciplines such as personal health, population health and planetary and health and this nutritional science concern the research and investigation of how an organism is nourished. New trends in food processing and technology affect the nutritional quality and quantity and the product manufacturing quality. Consumers around the world are better educated and more demanding in their identification and purchase of quality health promoting foods. The food industry and regulatory agencies are searching for innovative technologies to provide safe and stable foods for their clientele. Thermal pasteurization and commercial sterilization of foods provide safe and nutritious foods that, unfortunately, are often heated beyond a safety factor that results in unacceptable quality and nutrient retention. Most foods are thermally preserved by subjecting the products to heating temperatures for a few seconds to several minutes and these high-energy generally diminish the cooking flavors, the vitamins, essential nutrients, phenolics and bioactive other constituents in the food products. Non thermal processing facilitates the development of innovative food products not previously envisioned. Niche markets for food products and processes will receive greater attention in future years. Non thermal technologies successfully decontaminate, pasteurize and potentially pursue commercial sterilization of selected foods while retaining fresh-like quality and excellent nutrient retention. The quest for technologies to meet consumer expectations with optimum quality safe processed foods is a most important priority for future food science research. The relevant factors to consider when conducting research into novel non thermal and thermal technologies as: Target microorganisms to provide safety; target enzymes to extend quality shelf life; maximization of potential synergistic effects; alteration of quality attributes; engineering aspects; conservation of energy and water; potential for convenient scale-up of pilot scale processes; reliability and economics of technologies and consumer perception of the technologies. “The search for new approaches to processing foods should be driven, above all, to maximize safety, quality, convenience, costs and consumer wellness”. Non thermal processing includes less heating procedures and especially cold processing techniques such as high pressure processing (HHP), pulsed electrical field (PEF) and ultrasound. Each technique can be utilized either alone or in combination to optimize the product quality. In this speech content, recent research on high pressure processing, pulsed electrical field and ultrasound processed egg and egg products, fruit juices including apple and cranberry juices and some fruits including berries, grape pomace, olive and coconut.

Keynote Forum

Gary Stoner

Medical College of Wisconsin, USA

Keynote: Berries for cancer prevention

Time : 09:35-10:10

OMICS International Nutrition 2015 International Conference Keynote Speaker Gary Stoner photo
Biography:

Dr. Stoner is Professor of Medicine at the Medical College of Wisconsin (MCW) Division of Hematology and Oncology, specializing in the fields of chemical carcinogenesis and cancer chemoprevention. He serves as Director of the Molecular Carcinogenesis and Chemoprevention Program in the newly developing Cancer Center. Dr. Stoner joined MCW after nearly 20 years at the Ohio State University College of Medicine where he held the positions of Lucius Wing Endowed Chair in Cancer Research and Therapy, Associate Director for Basic Research and Director of the Chemoprevention Program in the Cancer Center, and Chair of the Division of Environmental Health Sciences and Associate Dean for Research in the College of Public Health.

Abstract:

A considerable amount of research has been conducted in the past two decades to evaluate the cancer preventative potential of berries. Most studies have utilized black raspberries, however, other berry types such as strawberries, blackberries, blueberries, red raspberries, acai and others are also capable of preventing cancer. Initially, a series of berry extracts were shown to reduce the proliferation rate of cancer cells in vitro and/or to stimulate apoptosis. The inhibitory potential of these extracts was often attributed to their content of ellagitannins or anthocyanins. Preclinical studies demonstrated that freeze-dried berry powders were effective in preventing chemical carcinogen-induced cancer in the rodent oral cavity, esophagus, and colon, and an anthocyanin-rich extract inhibited UV-induced skin cancer in mice. Mechanistic studies showed that the berries prevented the conversion of premalignant lesions in rodent tissues to malignancy by reducing cell proliferation, inflammation, and angiogenesis and by stimulating apoptosis and cell differentiation. Multiple genes associated with all of these cellular functions are protectively modulated by berries. For example, berries down-regulate the expression levels of genes in the P13K/Akt, MAPK, ERK ½, AP-1 and mTOR signaling pathways (proliferation), COX-2, iNOS, NF-κB, IL-1β and IL-12 (inflammation), VEGF and HIF-1α (angiogenesis), and upregulate caspase 3/7 and Bax (apoptosis), and both keratin- and mucus-associated genes for squamous and glandular differentiation, respectively. Bio-fractionation studies indicate that the most active inhibitory compounds in berries are the anthocyanins and ellagitannins. The fiber fraction of berries is also effective in preventing cancer in rodents and research is needed to identify the active polysaccharides in this fraction.rnHuman clinical trials indicate that freeze-dried berry formulations elicit little or no toxicity in humans when administered in the diet at concentrations as high as 60g/day for as long as nine months. The uptake of berry anthocyanins and ellagic acid into blood is rapid but minimal; i.e., less than 1% of the administered dose. Nearly 70% of the administered anthocyanins are metabolized by the enteric bacteria into protocatechuic acid (PCA) which has substantial cancer preventative activity. Black raspberry formulations have been shown to cause histologic regression of oral leukoplakic lesions in the oral cavity, dysplastic lesions in the esophagus, and polyps in the rectum of patients with familial adenomatous polyposis. These results are very promising and the mechanisms for these effects will be discussed. In addition, the advantages and challenges to the clinical application of utilizing berries for cancer prevention will be discussed and suggestions made for future trials.

Keynote Forum

Alison Burton Shepherd

De Montfort University, UK

Keynote: Preventing malnutrition in home dwelling elderly individuals

Time : 10:10-10:45

OMICS International Nutrition 2015 International Conference Keynote Speaker Alison Burton Shepherd photo
Biography:

Alison Burton Shepherd is a Senior Lecturer in Adult Nursing at De Montfort University, UK. In 2010, she became a Queens Nurse, which is an Award given for excellence in Nursing Care within the community setting. She works as an Advanced Nurse Practitioner and she is an Independent Nurse Prescriber. She is also an Inspector for the Care Quality Commission.

Abstract:

Undernutrition is common among older people generally and arguably malnutrition is considered to be a larger public health problem than that of obesity. At any point in time it estimated more than 3 million individuals in United Kingdom are at risk of developing malnutrition with approximately 93% of those living in their own homes. Latest data from the USA (Gerontological Society of America 2015) also asserts that one third to half of all US adults in the community setting aged 65 years and over are malnourished or are at risk of malnutrition upon admission to hospital. Malnutrition is associated with both increased morbidity and mortality. Therefore it is prudent to suggest that prevention is better than cure. This presentation will begin by examining some of the causes of malnutrition in the elderly. The remainder of the session provides an in depth focused discussion on the role of healthcare clinicians in its assessment and prevention and recommends ways in which clinical practice may be improved.

Break: Networking & Refreshments 10:45-11:05 @ Foyer
OMICS International Nutrition 2015 International Conference Keynote Speaker Li-Shu Wang photo
Biography:

Li-Shu Wang is an Assistant Professor of Medicine in the Division of Hematology and Oncology at the Medical College of Wisconsin (MCW). Her research interests are in the fields of chemical carcinogenesis and cancer chemoprevention. She received her PhD in Veterinary Biosciences from Ohio State University where her research was focused on illustrating the mechanisms of conjugated linoleic acid, naturally occurring compounds, in the prevention of breast cancers. Afterward, she continued involved in cancer prevention research as a Post-doctoral fellow and research scientist at the same university. During her Post-doctoral training, her research was focused on the prevention of gastrointestinal cancers using berries, their active components and metabolites. Her research is documented in more than 45 peer-reviewed publications and book chapters. She has received numerous awards including scholar-in-training award of American Association for Cancer Research (AACR) prevention meeting and IAMS research funds. She is a reviewer for several publications including but not limited to Cancer Research, Clinical Cancer Research, Cancer Epidemiology and Biomarkers & Prevention.

Abstract:

Although with improved understanding of the pathophysiology of pancreatic ductal adeno-carcinoma (PDAC) in the past two decades, PDAC remains one of the poorest prognostic tumors, with an extremely low 5-year survival rate (4.1%). Diets rich in fruits and vegetables have been reported to reduce the risk of cancer development. Our current study investigated the potential effects of BRBs against PDAC in mice. KrasLSL.G12D/+-Trp53LSL.R172H/+-Pdx-1-Cre mice spontaneously develop PDAC that recapitulates human PDAC. Four-week-old KrasLSL.G12D/+-Trp53LSL.R172H/+-Pdx-1-Cre mice bearing precancerous pancreatic intraepithelial neoplasia (PanIN) lesions were fed either control or 5% BRB diet. Kaplan-Meier survival analysis showed that BRBs significantly prolonged survival of PDAC mice. BRBs suppressed Raf/MEK/ERK/STAT3 pathways, downstream of Kras and inhibited cell proliferation in pancreatic tumors. In addition, BRBs significantly decreased the size of tumors produced by injecting luciferase-transfected human Panc-1 cells (Panc-1-Luc) into the pancreas of NOD.SCID mice. Orthotopic tumors in BRB-treated NOD.SCID mice had higher rate of apoptosis compared to tumors from mice fed control diet. These results support the hypothesis of a clinical potential of BRBs for the delay of pancreatic cancer progression through suppressing cancer cell proliferation and/or promoting apoptosis.

OMICS International Nutrition 2015 International Conference Keynote Speaker Talha Muezzinoglu photo
Biography:

Talha Müezzinoglu (Professor) is the Head of the Urology Department of Medical Faculty of Celal Bayar University. He completed his Bachelor’s (1991) science at Medical Faculty of Dokuz Eylul University, Izmir. He is currently working as full Professor in the Department of Urology of the Medical Faculty of Celal Bayar University as a faculty member from 2011 to date. He professionally officiated at Heildelberg University, Heillbronn Hospital, Germany, as a Research Associate at 2007 and also professionally officiated at Emory University, Atlanta, USA as a tranie scholar for robotic urological surgery. He organized various international attendee congress. His research interests range from prostate incidence and advanced uro-oncology techniques to life quality in urological cancers, cancer treatment methodologies. He has administrated and attended to several laparoscopy prostatectomy and laparascopic urology courses, clinical trials, research education programs in national and international countries. He served as health publisher and media partner for national newspapers for raising the awareness of public.

Abstract:

In this study, the concentrations of different trace metals, including Fe, Mg, Cd, Ni, Zn, Cu, Se, Ca and Boron (B) in malign and benign prostate tissues, were determined by Induced Coupled Plasma-Mass Spectroscopy and Induced Coupled Plasma-Optic Emission Spectroscopy. We also analyzed the relationship of these concentrations with histopathology stage, PSA and clinical survey. It was investigated the possible role of tissue trace element levels in development of prostate cancer and the relationship between histopathologic stage, preoperative PSA levels and biochemical PSA recurrences. Cd, Ni and Ca average concentrations were determined lower and Fe average concentration was determined higher in prostate cancer tissue, statistically (55.64 µg/kg, p=0.033; 784.02 µg/kg, p<0.001; 656.94 mg/kg, p<0.001 and 56.52 mg/kg, p=0.039, respectively). There was a negative correlation between B and total gleason score (p=0.003) and positive correlation between Se and total gleason score (p=0.002). Mg and Ca were determined higher and B was detected lower in tissues with neuro-vascular invasion (p=0.016, p=0.008 and p=0.033, respectively). Only Zn concentration was lower in cases with extra capsular extention then without (p=0.016). There was no any relationship or correlation between the concentration of trace elements and preoperative PSA levels, biochemical PSA recurrences, surgical margins and invasion of seminal vesicles. The increasing in Fe levels and decreasing in Cd, Ni, Ca, and theirs heterogeneous distribution in malign samples was very important for the investigation of cancer mechanisms. Besides, some of trace elements may effect of the prognosis of prostate cancer. In this context, more studies are needed regarding the increasing or decreasing in the trace element concentrations in malign prostate samples.