Nindy Sabrina
Taipei Medical University, Taiwan
Title: Calorie restriction combined with meal replacement is more effective to improve body weight and body composition in obesity
Biography
Biography: Nindy Sabrina
Abstract
Background: Recent evidence suggests that calorie restriction (CR) is more effective for obesity treatment that dietary fat restriction. Meal replacement (MR) also have shown as an effective strategy for the long term maintenance of weight loss compared with a traditional reduced calorie diet regimen. However, it is not clear whether combination between calorie restriction with meal replacement diet (CRMR) would promote favorable change in body weight and body composition. The aim of this study was to compare the effects of dietary intervention focusing on either calorie restriction alone or calorie restriction plus meal replacement on weight loss and body composition.
Subjects/Methods: The 99 eligible subjects were randomized to either 1500-kcal CR and CRMR groups for 12 weeks. The CRMR group was supplied with low-calorie nutrition drink mix powder. The changes in anthropometry and body composition were evaluated. Body composition was measured with dual energy x-ray absorptiometry (DEXA).
Results: Seventy subjects have completed the study. During weight loss period, body weight and body mass index (BMI) decreased similarly (P<0.001) in the CRMR group (-7.39 ± 5.09 %;-7.40 ± 5.10 %, respectively) and CR group (-2.31 ± 2.07 %; -2.31 ± 2.09 %, respectively). Waist circumference decreased similarly (P<0.001) in the CRMR and CR groups (-6.80 ± 7.59 % and -5.96 ± 4.80 % respectively). Fat mass decreased more (P<0.001) in the CRMR group (-15.99 ± 9.37 %) versus the CR group (-4.20 ± 6.82). Android fat and gynoid fat decreased similarly (P<0.001) in the CRMR group by -7.44 ± 7.82 % and -3.26 ± 7.16 %, respectively.
Conclusion: These findings suggest that CRMR is effective to body weight and body composition of obese in comparison with CR alone