29th World Congress on Nutrition and Food Sciences
Paris, France
Dr.Maria Papamichael
La Trobe University Greece
Title: Urinary metabolomics profile of Greek Asthmatic school-children
Biography
Biography: Dr.Maria Papamichael
Abstract
In clinical practice, biomarkers can provide complementary information to conventional pulmonary tests, symptoms, spirometry, exhaled nitric oxide, PC20 methacholine and histamine . They are useful in establishing diagnosis, monitoring of the disease progression and in response to treatment. The development of non-invasive sampling methods and detection techniques for the identification of components involved in airway inflammation including the determination of biomarkers would greatly contribute to our current insight in airway inflammation associated with various asthma phenotypes as well as to customize individually-targeted therapies. In children reliable non-invasive biomarkers would be valuable.
We applied metabolomic analysis to study the association between urinary organic acid concentrations and pulmonary function in 72 Caucasian children (5-12 years) with asthma determined by gas chromatography and mass.